The RocSite Discovery Engine identified that published ICU mortality estimates underestimate risk for elderly patients by 66–168% across three conditions simultaneously. Pre-registered. Cross-validated. 201,905 patients. Two independent datasets.
Dedicated engine instance against your proprietary data. Monthly contradiction reports. OSF pre-registration and evidence hashes for every finding. Your data stays in your environment.
Independent falsification testing of clinical AI models before FDA submission. Leakage detection, label stability, cross-dataset validation. Published methodology. Citable report.
We run the engine against your cohort. Joint analysis, co-authored publication, OSF pre-registration before any analysis runs. All code published openly.
Across MIMIC-IV and eICU-CRD — two independent datasets — observed ICU mortality for elderly MI patients is 21.5%. The commonly cited published estimate is 8.0%. That's not a rounding error. It's a clinical risk stratification failure that shapes bedside decisions and every model trained on the literature.
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